A Glance at G-Protein Coupled Receptors
G-Protein Receptors Subfamily G-Protein Receptors family indeed is a superfamily comprising of many subfamilies which include 7TM orphan receptors, vomeronasal receptors (VN1R and VN2R), Taste receptors (TAS1R and TAS2R), Class F frizzled (FZD), Class C metabotropic pheromone/glutamate, Class B secretin-like, and Class A rhodopsin-like. GPCRs are categorized into 7 subfamilies resting on the stimuli type, which activates the G-protein receptors and sequence similarity. Their activating ligands though differ widely in character and structure, the receptors amino acid sequences are quite similar and thus are believed in adopting a common structural framework that includes 7 transmembrane helices. Take a look at the G-Protein Receptors four main subfamilies, Class A rhodopsin-like G-Protein Receptors- This is the largest family and make up about 50% of all G-Protein Receptors, which includes light receptors, neurotransmitters, and hormones. All of the...